As a way to rationalise the noticed ABL kinase inhibitory results from the 3D structural viewpoint, the lead compounds I and II, as well as recently made derivatives 4a, 4b, and 5 were being docked within the catalytic kinase domains of BCR-ABLWT (PDB code: 3OXZ) and BCR-ABLT315I (PDB code: 3OY3)34. https://riverumdrg.alltdesign.com/the-5-second-trick-for-indazole-n-oxide-50716173