Having recognized the palmitoylation motif of APLNR, we designed a brief substrate sequence to competitively inhibit the palmitoylation of endogenous APLNR. This competitive peptide, which targets the APLNR palmitoylation web-site together with morphine, can inhibit the development of NCP, together with pain incidence, microglial activation, and inflammatory factor launch https://boysn515syz5.wikitron.com/user